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Background: At 14 years of age for boys and 13 years for girls, delayed puberty with low gonadotropic hormones can either be a chronopathologic feature (constitutional delay of puberty CDP) or the subclinical unmasking of a future isolated hypogonadotropic hypogonadism (IHH). The two conditions are difficult to differentiate at these specific ages.Objective and hypotheses: We aimed to identify clinical and paraclinical features which correlate wit...

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hrp0084p3-971 | GH & IGF | ESPE2015

Patients with Childhood Onset Growth Hormone Deficiency Treated with rhGH – Reevaluation in the Transition Period between Childhood and Adulthood – Preliminary Study

Procopiuc Camelia , Caragheorgheopol Andra , Gherlan Iuliana , Brehar Andreea , Padure Adriana , Dumitrascu Andra , Costache Mariana , Ardeleanu Ioana , Dumitrescu Crisina

Background: More than two thirds of teenagers with childhood-onset GH deficiency (CO-GHD) documented normal GH response when retested at final height.Objective and hypotheses: To identify potential predictors for persistent GHD after reaching final height under rhGH with a particular accent on children with isolated GHD (IGHD).Method: Prospective study: reevaluation CO-GHD in the transition period; cohort of 27 CO-GHD patient who r...

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ESPE Abstracts

Delayed Puberty: Between Chronopathology and Subclinical Pathology

Patients with Childhood Onset Growth Hormone Deficiency Treated with rhGH – Reevaluation in the Transition Period between Childhood and Adulthood – Preliminary Study

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